Optics: measuring and testing – Blood analysis
Patent
1977-07-14
1979-11-27
Marcus, Michael S.
Optics: measuring and testing
Blood analysis
356407, 364416, 422 68, G01N 3316
Patent
active
041758595
ABSTRACT:
An apparatus for automated classification of white blood cells comprising photo-electric converter means whereby the green and blue lights passing through the blood smear are converted into the respective electric signals, a first means for detecting the zone where the nucleus of white blood cell is present at a certain threshold level determined by the maximum and minimum values of the electric signal corresponding to green color, a second means for discriminating between the nucleus of white blood cell obtained from said first means and the granules and cytoplasm of white blood cell at a certain threshold level determined according to said electric signal corresponding to green color, a third means for discriminating between said cytoplasm and the back-ground at the threshold value determined on the basis of said electric signal corresponding to green color and obtained by adding a certain value to the average density on the back-ground, and a fourth means for discriminating between said nucleus and the red blood cells at a certain threshold level determined on the basis of said electric signal corresponding to blue color.
REFERENCES:
patent: 3315229 (1967-04-01), Smithline
patent: 3715601 (1973-02-01), Tucker
patent: 3851156 (1974-11-01), Green
patent: 3919530 (1975-11-01), Cheng
patent: 3969024 (1976-07-01), Hashizume et al.
patent: 3999047 (1976-12-01), Green
patent: 4000417 (1976-12-01), Adkisson et al.
patent: 4012634 (1977-03-01), Bouton et al.
Hashizume Akihide
Horiuchi Hideyuki
Suzuki Ryuichi
Yamamoto Shinji
Yokouchi Hisatake
Hitachi , Ltd.
Marcus Michael S.
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