Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Patent
1993-07-30
1996-01-30
Redding, David A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
435 31, 435 34, 422 62, 422 81, 422 82, 422 8202, 422 8209, 436 52, 436 53, 436 63, 436 71, 204403, C12Q 124, C12M 134
Patent
active
054879817
ABSTRACT:
An apparatus for and a method of on-line detecting and assessing, in situ, he amount and characterization of microbial trace contamination in an associated ultra-pure water system is disclosed. The apparatus comprises, inter alia, a monitor/detector portion and an assessment/identification portion. The monitor/detector portion includes a contamination mass detector which nondestructively senses the presence of microbial biofilms in real time when grown upon the surface of a quartz crystal wafer portion of the contamination mass detector. The assessment/identification portion is configured to provide quantitative analysis of the microbial biofilms formations based on signature biomarker cellular components. A programmable controller is configured to integrate these and other portions into an automated apparatus, which is capable of providing real time chemical countermeasures to prevent the potential deleterious effect of the microbial trace contamination uncovered.
REFERENCES:
patent: 4912332 (1990-03-01), Siebel et al.
patent: 5049492 (1991-09-01), Sauer et al.
patent: 5246560 (1993-09-01), Nekoksa et al.
Chambers James Q.
Nivens David E.
White David C.
McCarthy William F.
McDonald Thomas E.
Redding David A.
The United States of America as represented by the Secretary of
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