Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-10-18
2005-10-18
Forman, BJ (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S007100, C435S174000, C435S283100, C435S287200, C435S288700, C422S068100, C422S082050
Reexamination Certificate
active
06955878
ABSTRACT:
There is used at least one probe array obtained by arraying particles having various probes, respectively, fixed thereon (probe particles) in a definite order in a holder. A plurality of capillaries or grooves packed with various kinds, respectively, of probe particles are arrayed in parallel, and one of particles contained in each capillary or groove is injected into another capillary or groove to produce a probe array in which the various kinds of probe particles are arrayed in a constant and definite order. Various fluorophore-labeled DNA's are measured at the same time by attaching various probes to particles, respectively, of different sizes. A probe array composed of various fixed DNA probes can easily be produced, and there can be provided a probe array for detecting various DNA's which is composed of various fixed arbitrary DNA probes.
REFERENCES:
patent: 5069769 (1991-12-01), Fujimiya et al.
patent: 5804384 (1998-09-01), Muller et al.
patent: 5922617 (1999-07-01), Wang et al.
patent: 6007987 (1999-12-01), Cantor et al.
patent: 6017765 (2000-01-01), Yamada et al.
patent: 6054035 (2000-04-01), Kambara et al.
patent: 6060240 (2000-05-01), Kamb et al.
patent: 6277628 (2001-08-01), Johann et al.
patent: 6288220 (2001-09-01), Kambara et al.
patent: 6391562 (2002-05-01), Kambara et al.
patent: WO 96/04404 (1996-02-01), None
Science, vol. 251, Feb. 15, 1991, “Light-Directed, Spatially Addressable Parallel Chemical Synthesis”, S. Fodor et al, pp. 767-773.
Analytical Biochemistry, vol. 247, 1997, “Covalent Attachment of Hybridizable Oligonucleotides to Glass Supports”, B. Joos et al, pp. 96-101.
Proceeding of the National Academy of Sciences USA, vol. 93, May 1996, “DNA Analysis and Diagnostics on Oligonocleotide Microchips”, G. Yershov, e al, pp. 4913-4918.
Biophysical Journal, vol. 71, Aug. 1996, “scanning Tunneling Microscopy o Mercapto-Hexyl-Oligonucleotides Attached to Gold”, D. Rakesh et al, pp. 1079-1086.
Kambara Hideki
Okano Kazunori
Forman BJ
Hitachi , Ltd.
Mattingly ,Stanger ,Malur & Brundidge, P.C.
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