Apparatus and process for strengthening low density compression

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices

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424441, 424484, 264319, A61K 920

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active

056163444

ABSTRACT:
The present invention is a process for forming a low density compression dosage unit to provide increased strength. The process of the present invention includes compacting under bi-level compaction pressure to provide a continuous-volume dosage unit which has a first volume defining an edge portion of the unit and a density which is greater than a density of a second volume defining a non-edge portion of the unit. The present invention also includes the product resulting from the process and apparatus used to make such units.

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