Apparatus and process for rapidly characterizing and differentia

Details Apparatus and process for rapidly characterizing and differentia Apparatus and process for rapidly characterizing and differentia

1976-08-20

1979-11-06

Corbin, John K.

Optics: measuring and testing

For size of particles

By particle light scattering

250564, 250574, 356343, G01N 1502

Patent

active

041734157

ABSTRACT:
To characterize and differentiate large organic cells rapidly, individual particles are illuminated with monochromatic radiation of a wave length comparable to the size of the cell, producing a differential light scattering pattern about the illuminated cell. The pattern is sensed, preferably in the disclosed apparatus, by an array of detectors, and the sensed pattern employed as an identification and characterization of the cell. The pattern may be analyzed, or selected portions of the pattern employed, to differentiate cells embodying different features. The apparatus and process is especially useful for rapid identification and differentiation of leucocytes and other types of mammalian cells, the radiation for such analyses preferably being infrared radiation. A preferred structure for individually illuminating such cells with radiation and for sensing their differential light scattering pattern is disclosed.

REFERENCES:
patent: 3624835 (1971-11-01), Wyatt
patent: 3834818 (1974-09-01), Meric
Wyatt, "Differential Light Scattering: a Physical Method for Identifying Living Bacterial Cells," Applied Optics, vol. 7, pp. 1879-1896, Oct. 1968.
Bonner et al., "Fluorescence Activated Cell Sorting," Review of Scientific Instruments, vol. 43, pp. 404-409, Mar. 1972.

Affiliated with

Also associated with

Rating

Apparatus and process for rapidly characterizing and differentia does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Apparatus and process for rapidly characterizing and differentia, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus and process for rapidly characterizing and differentia will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-460132