Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds virus or component thereof
Patent
1986-09-23
1988-09-06
Meyers, Albert T.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Binds virus or component thereof
424127, 514672, 514753, 514832, 514833, A61K 3304, A61K 3306, A61K 3113, A61K 3103
Patent
active
047692413
ABSTRACT:
Perfluorocarbon emulsion formulations are oxygenated prior to use by means of a portable oxygenation system. The blood substitute is in a closed container or bag. An oxygen-containing gas is introduced into the bag from a separate container. The bag is continuously agitated for a sufficient time to increase the pO.sub.2 of the perfluorocarbon emulsion formulations to a desired pressure, e.g., to at least 600 mmHg. In one embodiment, the system used for oxygenation of the perfluorocarbon emulsion formulations comprises a small tank for gas having an inlet port and an outlet port fitted with shut-off valves. The outlet port is adapted to be connected to a filter which, in turn, is adapted to be connected to the inlet port of a three-way valve. The primary outlet of the three-way valve is adapted to mount a hypodermic needle which is adapted to be pushed through a rubber septum in a port of the bag to communicate with the interior of the bag. The tank is adapted to be filled with oxygen-containing gas, such as carbogen, from a main gas source under pressure. The tank, filter, three-way valve and needle arrangement are connected in series, and the oxygen-containing gas is permitted to flow from the tank into the bag holding the emulsion formulation. After the gas is introduced into the bag, the three-way valve is closed to prevent leakage of the gas from the container. The container is then agitated to oxygenate the emulsion formulation.
REFERENCES:
patent: 1808854 (1931-06-01), Malone
patent: 1943903 (1934-01-01), Treanor
patent: 2241018 (1941-05-01), Lloyd
patent: 2693802 (1954-11-01), Osborn
patent: 2702035 (1955-02-01), Gibbon
patent: 2827901 (1958-03-01), Jones
patent: 3015331 (1962-01-01), Warrick
patent: 3183908 (1965-05-01), Collins
patent: 3212499 (1965-10-01), Koreski
patent: 3276589 (1966-10-01), Jankay
patent: 3406531 (1968-10-01), Swenson et al.
patent: 3515640 (1970-06-01), Rudlin
patent: 3536451 (1970-10-01), Ludwin
patent: 3639084 (1972-02-01), Goldhaber
patent: 3733776 (1973-05-01), Li et al.
patent: 3832139 (1974-08-01), Runck et al.
patent: 3942527 (1976-03-01), Li et al.
patent: 3962439 (1976-06-01), Yokoyama et al.
patent: 4183962 (1980-01-01), Asher
patent: 4252827 (1981-02-01), Yokoyama et al.
patent: 4464337 (1984-08-01), Zelman
Crowe Kim C.
Davis, Jr. Charles H.
Groveman George R.
Heldebrant Charles M.
Alpha Therapeutic Corporation
Kilcoyne John M.
Meyers Albert T.
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