Chemistry: analytical and immunological testing – Including sample preparation
Patent
1996-09-23
1999-03-30
Pyon, Harold Y.
Chemistry: analytical and immunological testing
Including sample preparation
422 58, 422101, 436177, 436809, G01N 100, B01L 1100
Patent
active
058888306
ABSTRACT:
Multiple chemical reactions are performed in a plurality of reaction vessels mounted in inlets in a manifold valve block. The manifold valve block is connected to a channel block which is utilized in conjunction with a solvent delivery system as part of the reaction cycle. The solvent fluid is drained from the reaction vessels when valves in the manifold valve block are opened while applying a vacuum thereto. Optionally, a thermal block may be utilized in conjunction with the manifold valve block and the channel block to facilitate the reaction. Upon completion of the reactant cycle, the manifold valve block is disconnected from the channel block and connected to a cleavage block assembly which contains vials for collecting reaction products. The cleavage product is drained from the reaction vessels through the manifold valve block into the vials upon opening the valves in the manifold valve block and applying a vacuum to the channel block.
REFERENCES:
patent: 4051205 (1977-09-01), Grant
patent: 4493815 (1985-01-01), Fernwood et al.
patent: 4761381 (1988-08-01), Blatt et al.
patent: 4777021 (1988-10-01), Wertz et al.
patent: 4902481 (1990-02-01), Clark et al.
patent: 4927604 (1990-05-01), Mathus et al.
patent: 4963498 (1990-10-01), Hillman et al.
patent: 4981786 (1991-01-01), Dafforn
patent: 5100623 (1992-03-01), Friswell
patent: 5108704 (1992-04-01), Bowers et al.
patent: 5133939 (1992-07-01), Mahe
patent: 5141719 (1992-08-01), Fernwood et al.
patent: 5219528 (1993-06-01), Clark
patent: 5227137 (1993-07-01), Monti et al.
patent: 5252296 (1993-10-01), Zuckerman et al.
patent: 5472672 (1995-12-01), Brennan
patent: 5529756 (1996-06-01), Brennan
Gausepohl et al., "Multiple Reaction System for Automated Simultaneous Peptide Synthesis," Proceedings of the Twenty-First European Peptide Symposium, Platia d'Aro, Spain, pp. 206-207 (Sep. 2-8, 1990).
Patent Abstracts of Japan, vol. 8, No. 86 (p.-269) (Apr. 19, 1994).
Pharmaceutical Sciences, 1990, Chapter 104, p. 1878.
Dorland's Illustrated Medical Dictionary, Twenty-sixth Edition, 1981, pp. 459 and 759.
Gennaro, Alfonso R., Remington's, 18.sup.th Edition, p. 1302.
Buckman Brad O.
Chitty Andrew I.
Martin John T.
Mohan Raju
Morrissey Michael M.
Berlex Laboratories Inc.
Pyon Harold Y.
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