Chemistry: analytical and immunological testing – Automated chemical analysis – With aspirator of claimed structure
Patent
1998-07-29
1999-08-10
Le, Long V.
Chemistry: analytical and immunological testing
Automated chemical analysis
With aspirator of claimed structure
436 49, 436180, 422 63, 422 81, 422100, G01N 3510
Patent
active
059358599
ABSTRACT:
A mixture of beads from a combinatorial library is held in suspension either by inducing circulating flow of a liquid in a tapered vessel by rising air bubbles or by floating the beads at the interface between two immiscible liquids. Beads are selected individually from the suspension by drawing liquid into the tip of a needle having a circular opening smaller than the diameter of a bead. After a bead is captured on the tip of a needle, excess beads are jarred loose or washed away by flow of a solvent through a sheath surrounding the needle, and the needle is moved by a robotic manipulator to a well into which the bead is released.
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Elliott John Duncan
Gleason John Gerald
Leber Jack Dale
Simolike Gerald C.
King William T.
Kinzig Charles M.
Le Long V.
SmithKline Beecham Corporation
Venetianer Stephen A.
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