Surgery – Liquid medicament atomizer or sprayer – Ultrasonic
Patent
1995-08-31
1996-12-24
Millin, V.
Surgery
Liquid medicament atomizer or sprayer
Ultrasonic
12820014, 239406, A61M 1100
Patent
active
055865500
ABSTRACT:
The invention provides methods and apparatus for the delivery of therapeutic liquids to the respiratory system of a patient. In an exemplary embodiment, the apparatus includes a vibratable non-planar member having tapered apertures which produce droplets wherein about 70% of more of the droplets by weight have a size in the range from about 1 .mu.m to 6 .mu.m. The apparatus may further optionally include a breath sensor which detects the inspiratory flow rate and transmits a signal to vibrate the non-planar member at a frequency corresponding to the inspiratory flow rate. Optionally, the non-planar member may be included in a disposable mouthpiece assembly that is separate from the oscillator assembly. In this manner, the mouthpiece assembly may be discarded after use, while the oscillator assembly may be reused.
REFERENCES:
patent: 3812854 (1974-05-01), Michaels et al.
patent: 4119096 (1978-10-01), Drews
patent: 4159803 (1979-07-01), Cameto et al.
patent: 4268460 (1981-05-01), Boiarski et al.
patent: 4300546 (1981-11-01), Kruber
patent: 4301093 (1981-11-01), Eck
patent: 4334531 (1982-06-01), Reichl et al.
patent: 4338576 (1982-07-01), Takahashi et al.
patent: 4465234 (1984-08-01), Maehara et al.
patent: 4533082 (1985-08-01), Maehara et al.
patent: 4632311 (1986-12-01), Nakane et al.
patent: 4790479 (1988-12-01), Matsumoto et al.
patent: 4793339 (1988-12-01), Matsumoto et al.
patent: 4850543 (1989-07-01), Takahashi et al.
patent: 4887989 (1989-10-01), Drews et al.
patent: 4976259 (1990-12-01), Higson et al.
patent: 5063922 (1991-11-01), Hakkinen
patent: 5076266 (1991-12-01), Babaev
patent: 5139016 (1992-08-01), Waser
patent: 5152456 (1992-10-01), Ross et al.
patent: 5164740 (1992-11-01), Ivri
patent: 5170782 (1992-12-01), Kocinski
patent: 5261601 (1993-11-01), Ross et al.
patent: 5487378 (1996-01-01), Robertson et al.
D. C. Cipolla et al., "Assessment of Aerosol Delivery Systems for Recombinant Human Deoxyribonuclease," S.T.P. Pharma Sciences 4 (1) 50-62, 1994.
D. C. Cipolla et al., "Characterization of Aerosols of Human Recombinaint Deoxyribonuclease I (rhDNase) Generated by Jet Nebulizers," Pharmaceutical Research 11 (4) 491-498, 1994.
I. Gonda, "Therapeutic Aerosols," Pharmaceutics, The Sci. of Dosage Form Design, M. E. Aulton, 341-358, 1988.
Ivri Yehuda
Wu Cheng H.
Fluid Propulsion Technologies, Inc.
Millin V.
Raciti Eric P.
LandOfFree
Apparatus and methods for the delivery of therapeutic liquids to does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Apparatus and methods for the delivery of therapeutic liquids to, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus and methods for the delivery of therapeutic liquids to will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1173107