Apparatus and methods for stimulating revascularization and/or t

Details Apparatus and methods for stimulating revascularization and/or t Apparatus and methods for stimulating revascularization and/or t

1999-03-17

2000-09-19

Buiz, Michael

Surgery

Instruments

Cutting, puncturing or piercing

606159, 606 46, A61B 1700

Patent

active

061205206

ABSTRACT:
Apparatus and methods for stimulating revascularization and tissue growth are provided using an apparatus having a directable end region carrying a tissue piercing end effector. The apparatus optionally includes electrodes for depositing RF energy to form a controlled degree of scar tissue formation, means for delivering a controlled amount of a bioactive agent at the treatment site, or both.

REFERENCES:
patent: 4479896 (1984-10-01), Antoniades
patent: 4957742 (1990-09-01), Knighton
patent: 5834418 (1998-11-01), Brazeau et al.
patent: 5840059 (1998-11-01), March et al.
patent: 5846225 (1998-12-01), Rosengart et al.
patent: 5899874 (1999-05-01), Jonsson
patent: 5906594 (1999-05-01), Scarfone et al.
Fenton II, John W. et al., "Thrombin and Antithrombotics," Seminars in Thrombosis and Hemostasis, vol. 24, No. 2, 1998, pp. 87-91.
Folkman, Judah, "Angiogenic Therapy of the Human Heart," Circulation, 1998; 97:628-629.
Henry, Timothy D., "Can We really Grow New Blood Vessels," The Lancet, vol. 351, Jun. 20, 1998, pp. 1826-1827.
Knighton, David R. et al., "Role of Platelets and Fibrin in the Healing Sequence," Annals of Surgery, vol. 196, No. 4, Oct. 1982, pp. 379-388.
Losordo, Douglas W. et al., "Gene Therapy for Myocardial Angiogenesis Initial Clinical Results With Direct Myocardial Injection of phVEGF.sub.165 as Sole Therapy for Myocardial Ischemia," Circulation, 1998; 98: 2800-2804.
Maloney, James P. et al., "In Vitro Release of Vascular Endothelial Growth Factor During Platelet Aggregation," American Physiological Society, H1054-H1061, 1998.
Miyazono, Kohei et al., "Platelet-Derived Endothelial Cell Growth Factor," Progress in Growth Factor Research, vol. 3, 1991, pp. 207-217.
Pipili-Synetos, E. et al., "Evidence That Platelets Promote Tube Formation By Endothelial Cells on Matrigel," British Journal of Pharmacology, vol. 125, 1998, pp. 1252-1257.
Simons, Michael et al., "Food for Starving Hearts," Nature Medicine, vol. 2, No. 5, May 1996, pp. 519-520.
Tsopanoglou, Nikos E. et al., "Thrombin Promotes Angiogenesis By a Mechanism Independent of Fibrin Formation," American Physiological Society, 0363-6143/93, C1302-1307.
Verheul, Henk M.W. et al., "Platelet: Transporter of Vascular Endothelial Growth Factor," Clinical Cancer Research, vol. 3, Dec. 1997, pp. 2187-2190.
Wartiovaara, Ulla et al., "Peripheral Blood Platelets Express VEGF-C and VEGF Which Are Released During Platelet Activation," Thromb Haemost, 1998, 80:171-5.
A Collection of Abstracts, Society of Thoracic Surgeons, 1999.

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