Apparatus and methods for producing and using high-density...

Chemistry: molecular biology and microbiology – Apparatus – Bioreactor

Reexamination Certificate

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Reexamination Certificate

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07598075

ABSTRACT:
Disclosed and claimed is apparatus and methods for the growth of cells to high density, products therefrom and uses thereof. Also disclosed and claimed is the use of this method for the growth to high-density insect cells, such as theSpodoptera frugiperdaSf900+ cell line (ATCC: CRL 12579). Further disclosed is the infection of Sf900+ cells at high cell density with wild type and recombinant baculoviruses to produce baculovirus and DNA or gene or expression products.

REFERENCES:
patent: 5002890 (1991-03-01), Morrison
patent: 5605835 (1997-02-01), Hu et al.
patent: 5888807 (1999-03-01), Palsson et al.
patent: 6048727 (2000-04-01), Kopf

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