Liquid purification or separation – Processes – Including controlling process in response to a sensed condition
Patent
1999-05-27
2000-08-08
Kim, John
Liquid purification or separation
Processes
Including controlling process in response to a sensed condition
210 85, 210 86, 210 94, 210 97, 210143, 210739, 210782, 422 8205, 422 8206, 422105, 422107, 422108, 422 8209, 435 2, 435 3, 436 55, 436164, 436165, 494 1, G01N 2100
Patent
active
060997400
ABSTRACT:
An apparatus for separating a blood component, e.g., fibrin monomer, from blood or plasma comprises a container (110) with a reaction chamber for receiving the plasma, where said reaction chamber is defined by an outer wall and comprises means for supplying said reaction chamber with an agent for converting the fibrinogen content of the plasma into a non-cross-linked fibrin polymer. The apparatus comprises furthermore a device for centrifuging the reaction chamber with the plasma and said agent to a degree sufficient for separating the non-cross-linked fibrin polymer from the plasma, for depositing said polymer on the outer wall of the reaction chamber, and for expelling the remaining plasma from the reaction chamber. The container (110) comprises means for supplying the reaction chamber with a solvent for dissolving said non-cross-linked fibrin polymer. The apparatus comprises furthermore a measuring device (130) for measuring the amount of the deposit of the non-cross-linked fibrin polymer on the outer wall of the container (110), as well as a control unit (131) for controlling the addition of solvent in response to said amount of polymer.
REFERENCES:
patent: 4766083 (1988-08-01), Miyashita et al.
patent: 4777141 (1988-10-01), Calzi et al.
Holm Niels Erik
Jorgensen Glenn A.
Bristol--Myers Squibb Company
Furman Jr. Theodore R.
Kilcoyne John M.
Kim John
Krieger Stuart E.
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