Apparatus and methods for gene therapy

Details Apparatus and methods for gene therapy Apparatus and methods for gene therapy

1996-12-27

1998-11-17

McDermott, Corrine M.

Surgery

Means for introducing or removing material from body for...

Infrared, visible light, ultraviolet, x-ray or electrical...

604102, 606 15, 607116, A61N 130

Patent

active

058369058

ABSTRACT:
A method and apparatus are disclosed for the in vivo transfer of therapeutic genes to internal body sites. An operating head of a catheter or endoscope contains a particle bombardment device for accelerating DNA-coated particles into a target tissue. With either endoscopy or arterial catheterization, the operating head may be guided to diseased or deficient organs, or other lesions, and deliver the gene coated particles in a targeted manner. In one embodiment, a double balloon catheter is employed to isolate an intravasular space containing the lesion to be treated, with the space being cleared of blood and filled with gas before operation of the particle bombardment device. The method and apparatus may also be employed to deliver other therapeutic agents to intracellular targets.

REFERENCES:
patent: 5120657 (1992-06-01), McCabe et al.
patent: 5486170 (1996-01-01), Winston et al.
patent: 5507724 (1996-04-01), Hofmann et al.

Affiliated with

Also associated with

Rating

Apparatus and methods for gene therapy does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Apparatus and methods for gene therapy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus and methods for gene therapy will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-879259