Chemistry: analytical and immunological testing – Biological cellular material tested
Reexamination Certificate
2008-05-27
2008-05-27
Sines, Brian (Department: 1797)
Chemistry: analytical and immunological testing
Biological cellular material tested
C422S050000, C422S068100, C422S081000, C422S082000, C422S105000, C422S105000, C422S105000, C436S043000, C436S174000, C436S177000, C436S180000, C435S004000, C435S325000
Reexamination Certificate
active
07378280
ABSTRACT:
The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention include elastomeric components and comprise a main flow channel; a plurality of branch flow channels; a plurality of control channels; and a plurality of valves. Preferably, each of the valves comprises one of the control channels and an elastomeric segment that is deflectable into or retractable from the main or branch flow channel upon which the valve operates in response to an actuation force applied to the control channel.
REFERENCES:
patent: 3570515 (1971-03-01), Kinner
patent: 3747628 (1973-07-01), Holster et al.
patent: 4046159 (1977-09-01), Pegourie
patent: 4119368 (1978-10-01), Yamakazi
patent: 4153855 (1979-05-01), Feingold
patent: 4245673 (1981-01-01), Bouteille et al.
patent: 4344064 (1982-08-01), Bitler et al.
patent: 4434704 (1984-03-01), Surjaatmadja
patent: 4707237 (1987-11-01), Lepp et al.
patent: 4898582 (1990-02-01), Faste
patent: 4992312 (1991-02-01), Frisch
patent: 5085562 (1992-02-01), Van Lintel
patent: 5088515 (1992-02-01), Kamen
patent: 5091652 (1992-02-01), Mathies et al.
patent: 5096388 (1992-03-01), Weinberg
patent: 5126115 (1992-06-01), Fujita et al.
patent: 5164558 (1992-11-01), Huff et al.
patent: 5171132 (1992-12-01), Miyazaki
patent: 5224843 (1993-07-01), Van Lintel
patent: 5259737 (1993-11-01), Kamisuki et al.
patent: 5265327 (1993-11-01), Faris et al.
patent: 5290240 (1994-03-01), Horres, Jr.
patent: 5304487 (1994-04-01), Wilding et al.
patent: 5336062 (1994-08-01), Richter
patent: 5346372 (1994-09-01), Naruse et al.
patent: 5375979 (1994-12-01), Trah
patent: 5376252 (1994-12-01), Ekstrom
patent: 5400741 (1995-03-01), DeTitta et al.
patent: 5423287 (1995-06-01), Usami et al.
patent: 5529465 (1996-06-01), Zengerle et al.
patent: 5593130 (1997-01-01), Hansson et al.
patent: 5639423 (1997-06-01), Northrup et al.
patent: 5642015 (1997-06-01), Whitehead et al.
patent: 5646039 (1997-07-01), Northrup et al.
patent: 5659171 (1997-08-01), Young et al.
patent: 5660370 (1997-08-01), Webster
patent: 5674742 (1997-10-01), Northrup et al.
patent: 5681024 (1997-10-01), Lisec et al.
patent: 5705018 (1998-01-01), Hartley
patent: 5759014 (1998-06-01), Van Lintel
patent: 5775371 (1998-07-01), Pan et al.
patent: 5788468 (1998-08-01), Dewa et al.
patent: 5802856 (1998-09-01), Schaper et al.
patent: 5832165 (1998-11-01), Reichert et al.
patent: 5836750 (1998-11-01), Cabuz
patent: 5842787 (1998-12-01), Kopf-Sill et al.
patent: 5846396 (1998-12-01), Zanzucchi et al.
patent: 5858195 (1999-01-01), Ramsey
patent: 5863722 (1999-01-01), Brenner
patent: 5875817 (1999-03-01), Carter
patent: 5876187 (1999-03-01), Forster et al.
patent: 5876675 (1999-03-01), Kennedy
patent: 5876946 (1999-03-01), Burbaum et al.
patent: 5888778 (1999-03-01), Shuber
patent: 5922591 (1999-07-01), Anderson et al.
patent: 5922604 (1999-07-01), Stapelton et al.
patent: 5928880 (1999-07-01), Wilding et al.
patent: 5932799 (1999-08-01), Moles
patent: 5942443 (1999-08-01), Parce et al.
patent: 5958344 (1999-09-01), Levine et al.
patent: 5972639 (1999-10-01), Parandoosh
patent: 5976822 (1999-11-01), Landrum et al.
patent: 6004515 (1999-12-01), Parce et al.
patent: 6007309 (1999-12-01), Hartley
patent: 6007690 (1999-12-01), Nelson et al.
patent: 6015531 (2000-01-01), Colin et al.
patent: 6018616 (2000-01-01), Schaper et al.
patent: 6043080 (2000-03-01), Lipshutz et al.
patent: 6046056 (2000-04-01), Parce et al.
patent: 6048498 (2000-04-01), Kennedy
patent: 6062261 (2000-05-01), Jacobson et al.
patent: 6094274 (2000-07-01), Yokoi
patent: 6103537 (2000-08-01), Ullman et al.
patent: 6107044 (2000-08-01), Nikiforov
patent: 6123769 (2000-09-01), Sanjoh
patent: 6132580 (2000-10-01), Mathies et al.
patent: 6132685 (2000-10-01), Kercso et al.
patent: 6136212 (2000-10-01), Mastrangelo et al.
patent: 6146842 (2000-11-01), Josiah et al.
patent: 6150119 (2000-11-01), Kopf-Sill et al.
patent: 6150180 (2000-11-01), Parce et al.
patent: 6155282 (2000-12-01), Zachary et al.
patent: 6165694 (2000-12-01), Liu
patent: 6167910 (2001-01-01), Chow
patent: 6171850 (2001-01-01), Nagle et al.
patent: 6174365 (2001-01-01), Sanjoh
patent: 6174675 (2001-01-01), Chow et al.
patent: 6197595 (2001-03-01), Anderson et al.
patent: 6214246 (2001-04-01), Craighead
patent: 6221654 (2001-04-01), Quake et al.
patent: 6225109 (2001-05-01), Juncosa et al.
patent: 6227809 (2001-05-01), Forster et al.
patent: 6235471 (2001-05-01), Knapp et al.
patent: 6296673 (2001-10-01), Santarsiero et al.
patent: 6306659 (2001-10-01), Parce et al.
patent: 6321791 (2001-11-01), Chow
patent: 6344325 (2002-02-01), Quake et al.
patent: 6345502 (2002-02-01), Tai et al.
patent: 6355420 (2002-03-01), Chan
patent: 6361671 (2002-03-01), Mathies et al.
patent: 6408878 (2002-06-01), Unger et al.
patent: 6409832 (2002-06-01), Weigl et al.
patent: 6540895 (2003-04-01), Spence et al.
patent: 6767706 (2004-07-01), Quake et al.
patent: 2001/0041357 (2001-11-01), Fouillet et al.
patent: 2002/0124896 (2002-09-01), O'Connor et al.
patent: 2003/0008308 (2003-01-01), Enzelberger et al.
patent: 2003/0138829 (2003-07-01), Unger et al.
patent: 2003/0196695 (2003-10-01), O'Connor et al.
patent: 299 17 313 (2001-02-01), None
patent: 0 579 997 (1994-01-01), None
patent: 0 592 094 (1994-04-01), None
patent: 0 703 364 (1996-03-01), None
patent: 0 706 004 (1996-04-01), None
patent: 0 779 436 (1997-06-01), None
patent: 0 829 360 (1998-03-01), None
patent: 0 845 603 (1998-06-01), None
patent: 0 999 055 (2000-05-01), None
patent: 2 155 152 (1985-09-01), None
patent: 2 308 460 (1997-06-01), None
patent: WO 90/15070 (1990-12-01), None
patent: WO 92/16657 (1992-10-01), None
patent: WO 96/27025 (1996-09-01), None
patent: WO 97/27324 (1997-07-01), None
patent: WO 98/00231 (1998-01-01), None
patent: WO 98/04742 (1998-02-01), None
patent: WO 98/07069 (1998-02-01), None
patent: WO 98/45481 (1998-10-01), None
patent: WO 99/00655 (1999-01-01), None
patent: WO 99/04361 (1999-01-01), None
patent: WO 99/14311 (1999-03-01), None
patent: WO 99/17093 (1999-04-01), None
patent: WO 99/41015 (1999-08-01), None
patent: WO 99/52633 (1999-10-01), None
patent: WO 99/61888 (1999-12-01), None
patent: WO 00/00678 (2000-01-01), None
patent: WO 00/43748 (2000-07-01), None
patent: WO 00/53801 (2000-09-01), None
patent: WO 00/60345 (2000-10-01), None
patent: WO 00/68414 (2000-11-01), None
patent: WO 00/70082 (2000-11-01), None
patent: WO 01/01025 (2001-01-01), None
patent: WO 01/07061 (2001-02-01), None
patent: WO 01/09595 (2001-02-01), None
patent: WO 01/09595 (2001-02-01), None
patent: WO 01/24937 (2001-04-01), None
patent: WO 01/32930 (2001-05-01), None
patent: WO 02/00343 (2002-01-01), None
patent: WO 02/29106 (2002-04-01), None
patent: WO 02/30486 (2002-04-01), None
patent: WO 02/40874 (2002-05-01), None
patent: WO 02/43615 (2002-06-01), None
patent: WO 02/065005 (2002-08-01), None
patent: WO 02/072892 (2002-09-01), None
patent: WO 02/081729 (2002-10-01), None
patent: WO 02/081935 (2002-10-01), None
patent: WO 03/048295 (2003-06-01), None
Axelrod, Daniel “Cell-Substrate Contacts Illuminated by Total Internal Reflection Fluorescence” Journal of Cell Biology, Apr. 1981, pp. 141-145, vol. 89.
Benard et al., “A Titanium-Nickel Shape-Memory Alloy Actuated Micropump,” Proceedings of Transducers '97, 1997 International Conference on Solid-State Sensors and Actuators, held in Chicago, IL., Jun. 16-19, 1997, 1:361-364 (1997).
Bryzek et al.; “Micromachines on the March”, IEEE Spectrum, 1994, pp. 20-31, vol. 31, No. 5.
Buchaillot et al.; “Silicon nitride thin films Young's modulus determination by an optical non-destructive method”, Jpn. J Appl Phys, 1995, pp. L794-L797, vol. 36, No. 2:6B.
Burns et al., “An Integrated Nanoliter DNA Analysis Device,” Science, 282:484-487 (1998).
Chiu et al.; “Patterned Deposition of Cells and Proteins onto Surfaces by Using Three-Dimensional Microfluidic
Chou Hou-Pu
Quake Stephen R.
Scherer Axel
Thorsen Todd A.
Unger Marc A.
California Institute of Technology
Sines Brian
Townsend and Townsend / and Crew LLP
LandOfFree
Apparatus and methods for conducting assays and high... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Apparatus and methods for conducting assays and high..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus and methods for conducting assays and high... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2813334