Apparatus and method using a new reaction capsule

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is organic

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422 64, 435 7, 436807, 436808, G01N 3353, G01N 33545, G01N 3502

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active

048716839

ABSTRACT:
A system and method for performing a clinical assay, both including the use of a reaction capsule having a hydrophobic membrane which may be repeatedly wetted and rendered hydrophobic. A pressure differential across the membrane causes liquid flow therethrough to be initiated and the hydrophobic state is then achieved by flowing gas through the membrane. The system includes a turntable supporting a plurality of reaction capsules and eccentric means for agitating the turntable and capsules. The turntable is rotated to position the capsules at various processing stations, including sample introduction, reagent introduction, wash, substrate introduction and read stations. A single cylinder two-inlet valve may be used, one inlet connected to liquid and a second inlet connected to a gas source, to provide both liquid and gas flow through the membrane.

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Chemplast Zitex Catalog No. C100, Chemplast, Inc., Wayne, N. J.
Sturgeon and Rubio Abstract No. 498 in Clinical Chemistry, vol. 30, No. 6.

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