Apparatus and method to reduce restenosis after arterial interve

Details Apparatus and method to reduce restenosis after arterial interve Apparatus and method to reduce restenosis after arterial interve

1994-01-21

1996-04-02

Sykes, Angela D.

Surgery

Radioactive substance applied to body for therapy

Radioactive substance placed within body

128659, A61N 500

Patent

active

055036139

ABSTRACT:
An apparatus guided by a guidewire within a patient's artery for reducing restenosis after arterial intervention in the patient's artery. A radiation dose delivery wire with a radiation source encapsulated within its distal end is inserted into a blind lumen in a balloon catheter to deliver radiation to a target area of the patient's artery.

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Joseph Wiedermann, Jeffrey Leavy, Howard Amols, Allan Schwartz, Shunichi Homma, Charles Marboe, Judah Weinberger; "Effects of High Dose Intracoronary Irradiation on Vasomotor Function and Smooth Muscle Histopathology". AHA, Oct. 1992.
Joseph G. Widermann, Charles Marboe, Howard Amols, Allan Schwartz, Judah Weinberger; "Intracoronary Irradiation Markedly Reduces Restenosis After Ballon Angioplasty in a Porcine Model". AHA, Oct. 1993.

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