Surgery – Instruments – Light application
Patent
1998-04-13
1999-12-07
Dvorak, Linda C. M.
Surgery
Instruments
Light application
606 2, 606 20, 607 80, 607 89, A61B 1736
Patent
active
05997530&
ABSTRACT:
Cryogen spray cooling of skin surface with millisecond cryogen spurts is an effective method for establishing a controlled temperature distribution in tissue and protecting the epidermis from nonspecific thermal injury during laser mediated dermatological procedures. Control of humidity level, spraying distance and cryogen boiling point is material to the resulting surface temperature. Decreasing the ambient humidity level results in less ice formation on the skin surface without altering the surface temperature during the cryogen spurt. For a particular delivery nozzle, increasing the spraying distance to 85 millimeters lowers the surface temperature. The methodology comprises establishing a controlled humidity level in the theater of operation of the irradiation site of the biological tissues before and/or during the cryogenic spray cooling of the biological tissue. At cold temperatures calibration was achieved by mounting a thermistor on a thermoelectric cooler. The thermal electric cooler was cooled from from 20.degree. C. to about -20.degree. C. while measuring its infrared emission.
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Anvari Bahman
Milner Thomas E.
Nelson J. Stuart
Tanenbaum B. Samuel
Dawes Daniel L.
Dvorak Linda C. M.
The Regents of the University of California
Yarnell Bryan
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