Apparatus and method of delivery of gas-supersaturated liquids

Surgery – Means for introducing or removing material from body for... – Gas application

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604 24, 604 21, 604264, A61M 3700

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active

055992960

ABSTRACT:
An apparatus 10 for delivery of a gas, such as oxygen, solution into an environment (such as a coronary artery). The apparatus includes a high pressure tubular housing 12 defining a lumen 14 therewithin. A plurality of axially disposed concentric tubes 16 are supported within the lumen 14. Each defines an annular space 18 between adjacent tubes. One or more supports 20 extend radially inwardly from the tubular housing 12. The supports are connected to the concentric tubes 16 to prevent radially or axially migration thereof during high pressure infusion of the oxygen supersaturated physiologic solution. The method includes the steps of compressing a carrier to form a compressed carrier for transporting the gas to eliminate gas nuclei before exposure of the carrier to the gas; exposing the compressed carrier to the gas under pressure to form a gas-saturated compressed carrier; transporting the gas-saturated compressed carrier to the delivery system; and infusing the gas supersaturated compressed carrier from the delivery system at an exit port to the environment without associated bubble formation and cavitation proximate the exit port so that the gas is transported to the site within the environment in solution with the carrier in a supersaturated state, the gas being liberated therefrom remote from the exit port upon arrival at the site within the environment.

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