Surgery – Diagnostic testing – Respiratory
Reexamination Certificate
2005-03-15
2005-03-15
Nasser, Robert L. (Department: 3736)
Surgery
Diagnostic testing
Respiratory
C073S023300, C600S538000
Reexamination Certificate
active
06866637
ABSTRACT:
The invention provides an estimation of key flow-independent parameters characteristic of NO exchange in the lungs, namely: 1) the steady state alveolar concentration, Calv,ss; 2) the maximum flux of NO from the airways, JNO,max; and 3) the diffusing capacity of NO in the airways, DNO,air. The parameters were estimated from a single exhalation maneuver comprised of a pre-expiratory breathhold, followed by an exhalation in which the flow rate progressively decreased. The mean values for JNO,max, DNO,air, and Calv,ssdo not depend on breathhold time for breathhold times greater than approximately 10 seconds.A prioriestimates of the parameter confidence intervals demonstrates that a breathhold no longer than 20 seconds may be adequate, and that JNO,maxbe can estimated with the smallest uncertainty, and DNO,airthe largest.
REFERENCES:
patent: 5447165 (1995-09-01), Gustafsson
patent: 5922610 (1999-07-01), Alving et al.
patent: 6010459 (2000-01-01), Silkoff et al.
patent: 6033368 (2000-03-01), Gaston et al.
patent: 6038913 (2000-03-01), Gustafsson et al.
patent: 6099480 (2000-08-01), Gustafsson
patent: 6612306 (2003-09-01), Mault
George Steven C.
Tsoukias Nikolaos
Dawes Daniel L.
Myers Dawes Andras & Sherman LLP
Nasser Robert L.
The Regents of the University of California
LandOfFree
Apparatus and method for the estimation of flow -independent... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Apparatus and method for the estimation of flow -independent..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus and method for the estimation of flow -independent... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3451819