Chemistry: molecular biology and microbiology – Miscellaneous
Patent
1988-10-21
1989-12-19
Kamen, Noah P.
Chemistry: molecular biology and microbiology
Miscellaneous
435286, C12M 102
Patent
active
048882941
ABSTRACT:
Cultivation tank (1) for continuous cultivation of cells or micro-organisms, containing a rotating separating device (11,12) for separating suspended cells from cultivation liquid (10) supplied continuously through a supply (4) and passed through the separating device (11,12) from the outside to the inside, cell free liquid being continuously discharged from within the separating device (11,12), the rotating parts (11,12) of the separating device being formed so that within the outer circumference a zone (15) is formed of a vortex-free, vertical rotating column of cultivation liquid from which the cells are radially thrown out by centrifugal forces into the surrounding liquid (10) through openings in the outlet circumference (11) of the separating device (11,12) are considerably greater than the size of the cells.
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Use of a Rotating Wire Cage for Retention of Animal Cells in a Perfusion Fermentor, R. Varecka and W. Scheirer, Develop. Biol. Standard., vol. 66, pp. 269-272, 5-1987.
De Haan Hans H.
van Wezel, deceased Antonius L.
Vermeij Stephan
Kamen Noah P.
Nederlanden Vertegenwoordigd
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