Apparatus and method for spotting a substrate

Coating apparatus – Immersion or work-confined pool type – Capillary passages or barometric column feed

Reexamination Certificate

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Details

C118S411000, C118S412000, C427S002110

Reexamination Certificate

active

11038334

ABSTRACT:
The present invention provides a method and apparatus for dispensing a small volume of a selected liquid, such as a biological sample or reagent, onto a substrate. The device includes a tube adapted to contain the liquid. An elongated fiber is disposed within the tube for axial movement therein between raised and lowered positions. Upon shifting or oscillating the fiber between its raised and lowered positions, a liquid spot can be formed at a selected position on the substrate. The device is readily adaptable for the production of micro-arrays having a great number of individual spots.

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