Apparatus and method for spotting a substrate

Details Apparatus and method for spotting a substrate Apparatus and method for spotting a substrate

2005-02-01

2005-02-01

Sells, James (Department: 1734)

Coating apparatus

Immersion or work-confined pool type

Capillary passages or barometric column feed

C118S411000, C118S412000

Reexamination Certificate

active

06849127

ABSTRACT:
The present invention provides a method and apparatus for dispensing a small volume of a selected liquid, such as a biological sample or reagent, onto a substrate. The device includes a tube adapted to contain the liquid. An elongate fiber is disposed within the tube for axial movement therein between raised and lowered positions. Upon shifting or oscillating the fiber between its raised and lowered positions, a liquid spot can be formed at a selected position on the substrate. The device is readily adaptable for the production of micro-arrays having a great number of individual spots.

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Co-pending U.S. patent application No. 09/506870 filed Feb. 15, 2000.

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