APPARATUS AND METHOD FOR SEPARATION OF BLOOD

Liquid purification or separation – Flow – fluid pressure or material level – responsive – Check valve

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210DIG23, 210359, 210446, B01d 3300

Patent

active

040574997

ABSTRACT:
An apparatus for the separation and collection of plasma or serum from the cellular phase of a blood sample in a blood collection tube having a piston assembly provided with a cup shaped housing with a closed rear portion having a one-way valve extending therethrough with a filter disposed in the housing and formed with an open forward portion surrounded by a flexible peripheral flange of greater diameter than the internal diameter of the collection tube. The invention also contemplates the provision of a piston assembly for use in apparatus for the separation and collection of plasma or serum in which the piston has a body member with a portion which permits the passage of the liquid phase and also has a peripheral projecting flexible flange of greater diameter than the internal diameter of the collection tube and having a smooth lower surface and a radially grooved upper surface so that when the piston assembly is shifted into the collection tube the lower surface of the flange has sealing wiping engagement with the inner wall of the container and the liquid phase will be forced through the central body portion of the piston assembly to be isolated on the other side thereof and so that when the piston is shifted outwardly the seal will be broken and the upper grooved surface of the flange engages the inner wall of the collection tube so that air can bypass through the grooves to the inner portion of the collection tube.

REFERENCES:
patent: 3481477 (1969-12-01), Farr
patent: 3586064 (1971-06-01), Brown
patent: 3661265 (1972-05-01), Greenspan
patent: 3693804 (1972-09-01), Grover
patent: 3761408 (1973-09-01), Lee

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