Imperforate bowl: centrifugal separators – Rotatable bowl – Including flexible – removable lining therein
Patent
1994-01-12
1994-11-29
Jenkins, Robert W.
Imperforate bowl: centrifugal separators
Rotatable bowl
Including flexible, removable lining therein
494 35, B04B 1100
Patent
active
053685423
ABSTRACT:
An apparatus and method for the separation of a predetermined type of microscopic unit (e.g., islets of Langerhans) from a given medium (e.g., pancreatic digest) by centrifuging in a substantially continuous density gradient. In one embodiment, a substantially continuous density gradient solution is provided to a flexible processing bag appropriately positioned within an upper chamber of a rotating variable volume centrifuge. The solution having a plurality of the desired microscopic units therein is loaded onto the gradient and such units migrate to a particular radial position within the gradient based upon the density of such units. Once appropriately separated by the formation of regions, a fluid is provided to a lower chamber of the centrifuge bowl during continued rotation thereof to sequentially remove fractions from the processing bag from an inward location to an outward location, at least one of which fractions includes the band of the desired microscopic units. The desired microscopic units of a given fraction(s) may therefore be provided to an appropriate collector.
London Nicholas
McMannis John D.
Cobe Laboratories, Inc.
Jenkins Robert W.
LandOfFree
Apparatus and method for separating microscopic units in a subst does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Apparatus and method for separating microscopic units in a subst, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus and method for separating microscopic units in a subst will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-70792