Apparatus and method for providing assay calibration data

Details Apparatus and method for providing assay calibration data Apparatus and method for providing assay calibration data

1992-10-27

1994-05-10

Envall, Jr., Roy N.

Boots, shoes, and leggings

422102, 356 39, G06F 1500

Patent

active

053114264

ABSTRACT:
A semi-automated biological sample analyzer and subsystems are provided to simultaneously perform a plurality of enzyme immuno assays for human IgE class antibodies specific to a panel of preselected allergens in each of a plurality of biological samples. A carousel is provided to position and hold a plurality of reaction cartridges. Each reaction cartridge includes a plurality of isolated test sites formed in a two dimensional array in a solid phase binding layer contained within a reaction well which is adapted to contain a biological sample to be assayed. The carousel and cartridges contain structures which cooperate to precisely position the cartridges in each of three separate dimensions so that each cartridge is positioned uniformly. An optical reader operating on a principle of diffuse reflectance is provided to read the results of the assays from each test site of each cartridge. Also provided is a subsystem which provides predetermined lot-specific assay calibration data which is useful for normalizing the results of various assays with respect to predetermined common standard values.

REFERENCES:
patent: 3680967 (1972-08-01), Engelhardt
patent: 3838251 (1974-09-01), Herrin
patent: 3892949 (1975-07-01), Dodson, III
patent: 3892950 (1975-07-01), Dodson, III
patent: 3938961 (1976-02-01), Lanier
patent: 4061469 (1977-12-01), DuBose
patent: 4115010 (1978-09-01), McAleer et al.
patent: 4115861 (1978-09-01), Allington
patent: 4148607 (1979-04-01), Bernoco et al.
patent: 4158435 (1979-06-01), Nakanishi et al.
patent: 4197088 (1980-04-01), Meserol et al.
patent: 4219152 (1980-08-01), Couch et al.
patent: 4230265 (1980-10-01), Casaly
patent: 4281387 (1981-07-01), Kraft et al.
patent: 4319271 (1982-03-01), Hurni et al.
patent: 4332788 (1982-06-01), Mochida et al.
patent: 4337517 (1982-06-01), Nickel et al.
patent: 4387298 (1983-06-01), Peterson et al.
patent: 4402088 (1983-08-01), McWaters et al.
patent: 4408344 (1983-10-01), McWaters et al.
patent: 4436812 (1984-03-01), Endoh et al.
patent: 4443117 (1984-04-01), Muramoto et al.
patent: 4453220 (1984-06-01), Flegal et al.
patent: 4488678 (1984-12-01), Hara et al.
patent: 4542528 (1985-09-01), Sanner et al.
patent: 4567361 (1986-01-01), Rosenthal
patent: 4568184 (1986-02-01), Krantz et al.
patent: 4580895 (1986-04-01), Patel
patent: 4685059 (1987-08-01), Yamamoto
patent: 4710031 (1987-12-01), Kelley et al.
patent: 4727033 (1988-02-01), Hijikata et al.
patent: 4810096 (1989-03-01), Russel et al.
patent: 4843021 (1989-06-01), Noguchi et al.
patent: 4977078 (1990-12-01), Niimura et al.
patent: 5075077 (1991-12-01), Durley, III et al.
Dan Monroe, Immunoassay, Dept of Med, Jul. 1984, pp. 921-931.
Chromatography Electrophoresis, Immunochemistry Molecular Biology HPLC, Bio Rad, Price List P, Mar. 1990.

Affiliated with

Also associated with

Rating

Apparatus and method for providing assay calibration data does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Apparatus and method for providing assay calibration data, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus and method for providing assay calibration data will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2416415