Apparatus and method for preparing small tissue samples for hist

Details Apparatus and method for preparing small tissue samples for hist Apparatus and method for preparing small tissue samples for hist

1998-04-14

1999-07-27

Redding, David A.

Chemistry: molecular biology and microbiology

Apparatus

Differentiated tissue perfusion or preservation apparatus

4353071, 425117, C12M 300

Patent

active

059289341

ABSTRACT:
The present invention is directed to a cassette for use in the preparation of small specimens for histological examination. While the cassette of the present invention is particularly adapted for use with small specimens, it is equally suitable for use in the processing of large specimens. The cassette includes an open container having a bottom wall, two side walls, a front wall and a back wall. The bottom wall has a plurality of first apertures disposed in the wall for passage of fluid through the cassette in a direction orthogonal to the plane of the bottom wall. At least two of the other walls also have a plurality of second apertures for the passage of fluid through the cassette in a direction parallel to the plane of the bottom wall. Each of the back wall, side walls and front wall are disposed at an angle outwardly from the bottom wall. All of the apertures of the cassette bottom, top and inner side walls have a longest dimension no greater than about 0.5 mm. Each of the first apertures and the second apertures can be any suitable shape such as round, oval, square or rectangular so long as the longest dimension of the aperture is less than about 0.5 mm. Another feature of the invention is that the walls comprising the apertures of the bottom wall are disposed at an angle inwardly from the interior floor of the bottom wall.

REFERENCES:
patent: 5061452 (1991-10-01), Yamamoto et al.
patent: 5080040 (1992-01-01), McCormick
patent: 5424040 (1995-06-01), Bjornsson
patent: 5427742 (1995-06-01), Holland
patent: 5543114 (1996-08-01), Dudek

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