Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Synthesis of peptides
Patent
1995-01-20
1997-03-25
Russel, Jeffrey E.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Synthesis of peptides
395906, 422116, 525 5411, B01J 802, C07K 104, C08F28300
Patent
active
056146086
ABSTRACT:
A solid phase synthesis system is provided by employing a fully automated robot that operates with a novel timing protocol for handling multiple synthetic tasks efficiently. The novel timing protocol is realized by performing steps in the synthesis cycles for different compounds, such as peptides, concurrently rather than on a sequential basis.
REFERENCES:
patent: 5147608 (1992-09-01), Hudson et al.
patent: 5368823 (1994-11-01), McGraw et al.
Biochem. Soc. Trans., vol. 20, issued 1992, Fox, "Automatic Multiple peptide synthesis", pp. 851-853.
Tetrahedron, vol. 45, No. 24, issued 1989, Schnorrenberg et al, "Fully Automatic Simultaneous Multiple . . . ", pp. 7759-7764.
Int. J. Peptide Protein Res., vol. 40, issued 1992, Zuckermann et al, "Design, construction and application . . . ", pp. 497-506.
Krchnak Viktor
Lebl Michal
Seligmann Bruce
Russel Jeffrey E.
Selectide Corporation
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