Apparatus and method for measuring the concentration of meconium

Details Apparatus and method for measuring the concentration of meconium Apparatus and method for measuring the concentration of meconium

1998-10-08

2000-03-28

Winakur, Eric F.

Surgery

Diagnostic testing

Measuring or detecting nonradioactive constituent of body...

600309, A61B 500

Patent

active

060442840

ABSTRACT:
In an apparatus and method for measuring in vitro the concentration of meconium in amniotic fluid, a plurality of sensors are placed in predetermined locations throughout an amniotic sac. Each sensor includes a blue light-emitting diode having a peak transmission wavelength centered at about 430 nm, a transducer comprising a blue-enhanced photodiode for converting the light received from the light-emitting diode to a voltage signal, and an operational amplifier for amplifying the voltage signal. The light source and transducer are spaced a predetermined distance relative to each other, and define an amniotic fluid passageway therebetween for receiving the amniotic fluid. A micro-controller calculates, in accordance with an empirically-determined linear equation, the meconium concentration based on the natural log of each transducer signal. The transducer signals are continuously converted to meconium concentration readings, and generated on a display to provide a continuous, real-time, quantitative and/or qualitative assessment of the presence of, and concentration of meconium in a plurality of locations within the amniotic sac.

REFERENCES:
patent: 5713351 (1998-02-01), Billings et al.
Molcho et al., "Spectrophotometric Determination of Meconium Concentration in Amniotic Fluid," Journal of Biomedical Engineering, vol. 8, No. 2, pp. 162-165, Apr. 1986.

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