Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is organic
Patent
1991-10-01
1995-06-27
Scheiner, Toni R.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is organic
356244, 356246, 422 58, 422 72, 422 73, 422101, 422102, 436164, 436165, 436172, 436531, 436533, 436536, 436538, 436541, 436805, 436807, 436808, 436809, 436810, 436824, 436908, G01N 33546
Patent
active
054279593
ABSTRACT:
On a slab-like board formed of a transparent material is closely attached a wedge-shaped transparent cover member provided with a recess in a central inner portion, thereby to form a clearance. The height of the clearance between the recess and the board is configured to decrease continuously or in steps. When an immunological active substance such as a monoclonal antibody is caused to sensitize carrier particles F, and a reagent having the carrier particles F dispersed into a liquid medium mainly composed of the water is mixed with a specimen, the reaction will occur in which the flocculate is formed from plural carrier particles. When this reaction liquid is poured into the clearance through the opening, the reaction liquid penetrates in the direction having a narrower vertical spacing due to surface tension. A single carrier particle unflocculated can move deep within the recess because it is small in diameter, but the flocculate G is trapped on its way and can not move because of its size.
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Miyazaki Takeshi
Nishimura Matsuomi
Ohnishi Toshikazu
Takayama Hidehito
Tanaka Kazumi
Canon Kabushiki Kaisha
Chin Christopher L.
Scheiner Toni R.
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