Radiant energy – Ionic separation or analysis – Ion beam pulsing means with detector synchronizing means
Patent
1993-05-26
1994-12-27
Hannaher, Constantine
Radiant energy
Ionic separation or analysis
Ion beam pulsing means with detector synchronizing means
250282, 250288, H01J 4940
Patent
active
053767888
ABSTRACT:
An improved apparatus and method for the analysis of ions generated by matrix-assisted laser desorption is disclosed. This apparatus and method enhances the mass spectral resolution compared to previous devices and methods by producing electrical modulation of the kinetic energy imparted to the generated ions in a matrix-assisted laser desorption mass spectrometer. This modulation causes parent ions of interest to be substantially reflected (and detected) or substantially not reflected (and not detected) within the spectrometer, while fragment ions produced from the parent ion of interest are substantially reflected (and detected) independent of said modulation. A difference signal is generated between electrical signals sensed when the parent ions are reflected and electrical signals sensed when the parent ions are not reflected thereby mitigating the effects on the mass spectrum of the undesired fragment ions.
REFERENCES:
patent: 4472631 (1984-09-01), Enke et al.
patent: 4694168 (1987-09-01), Le Beyer et al.
patent: 5045694 (1991-09-01), Beavu et al.
patent: 5144127 (1992-09-01), Williams et al.
patent: 5160840 (1992-11-01), Vestal
patent: 5202563 (1993-04-01), Cotter et al.
Ens Werner
Standing Kenneth G.
Beyer James
Cook Paul J.
Hannaher Constantine
Jones Huw R.
Karnakis Andrew T.
LandOfFree
Apparatus and method for matrix-assisted laser desorption mass s does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Apparatus and method for matrix-assisted laser desorption mass s, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus and method for matrix-assisted laser desorption mass s will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-920725