Apparatus and method for lyophilizing aseptic substances

Details Apparatus and method for lyophilizing aseptic substances Apparatus and method for lyophilizing aseptic substances

1980-03-03

1981-09-01

Camby, John J.

Drying and gas or vapor contact with solids

Apparatus

With means to treat gas or vapor

215307, 215364, F27B 506

Patent

active

042863899

ABSTRACT:
Apparatus for use in lyophilizing a substance in a container and sealing the substance within the container after lyophilization. The apparatus includes an upper portion positionable about a resilient stopper in frictional engagement therewith, and a structure supporting the upper portion. The supporting structure is positionable on the open end of the container to space the upper portion and the stopper axially therefrom and define at least one fluid path communicating with the interior of the container. The upper portion and the supporting means may define an axial passageway for conducting the stopper from the initial position to a sealing position at least partially within the open end of the container upon application of an axial force to the stopper.

REFERENCES:
patent: 649012 (1900-05-01), Tapscott
patent: 718659 (1903-01-01), Ruffin
patent: 3247995 (1966-04-01), Jensen
patent: 3338447 (1967-08-01), Meyers, Jr.
patent: 3578195 (1971-05-01), Ogle
patent: 3795986 (1974-03-01), Sutherland et al.
patent: 3834571 (1974-09-01), Bartell
patent: 4193402 (1980-03-01), Rumpler

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