Apparatus and method for liquid chromatography

Liquid purification or separation – Processes – Chromatography

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210741, 210101, 2101982, B01D 1508

Patent

active

047691530

ABSTRACT:
To stabilize flow rate in a single-stroke, syringe-type high pressure pump to a constant value after turn-on, a control system increases the pump speed until equilibrium conditions are reached and then pumps at the preset rate. The pumping system is operated at a flow rate ten times the preset flow rate. The control system senses the maximum rate of change of pressure, detects when the rate of change has dropped to nine-tenths of the maximum and, when the time derivative of the pressure has dropped to nine tenths of its maximum, the pump motor speed is reduced to the preset flow rate.

REFERENCES:
patent: 4043906 (1977-08-01), Helmer
patent: 4128476 (1978-12-01), Rock
patent: 4233156 (1980-11-01), Tsukada et al.
patent: 4237422 (1980-12-01), Lenhardt
patent: 4448692 (1984-05-01), Nakamoto et al.

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