Apparatus and method for ion fragmentation cut-off

Radiant energy – Ionic separation or analysis – Cyclically varying ion selecting field means

Reexamination Certificate

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C250S282000, C250S281000, C250S288000

Reexamination Certificate

active

11069629

ABSTRACT:
A mass analyzer for isolating, fragmenting and scanning ions. The mass analyzer includes an ion trap having a first electrode, a second electrode adjacent to the first electrode, and a third electrode interposed between the first electrode and the second electrode, a first RF source electrically connected to the first electrode and second electrode and a second RF voltage source electrically connected to the third electrode. The second RF voltage source provides for a second electrical field for fragmenting ions and broadens the potential application of the fragmentation cut-off of the device allowing for analysis of peptides and other complex molecules. The mass analyzer may be used independently or in combination with a mass spectrometry system. A method of ion fragmentation and cut-off is also disclosed.

REFERENCES:
patent: 5696376 (1997-12-01), Doroshenko et al.
patent: 5793038 (1998-08-01), Buttrill, Jr.
patent: 2005/0167585 (2005-08-01), Makarov et al.

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