Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1983-02-03
1985-08-27
Marantz, Sidney
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
356317, 356318, 356417, 436519, 436524, 436525, 436526, 436535, 436805, 436807, G01N 3354, G01N 3358
Patent
active
045378614
ABSTRACT:
Apparatus and method for an immunoassay of a binding reaction between a ligand and an antiligand which are typically an antigen and an antibody, including a spatial pattern formed by a spatial array of separate regions of antiligand material, and ligand material dispersed to interact with the spatial array of separate regions of antiligand material for producing a binding reaction between the ligand and the antiligand in the spatial patterns and with the bound complexes labeled with a particular physical characteristic. A source of input energy and with the input energy at a particular spectrum for interacting with particular physical characteristic of the labeled binding reaction. Scanning the spatial pattern with the input energy at the particular spectrum for producing output energy having amplitude levels formed by a substantially random background component and a non-random component representing the labeled bound complexes, and the non-random component representing the labeled bound complexes detected to produce an output signal in accordance with the labeled binding reaction.
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Wear, 29, (1974), pp. 41-47, "Measurement of Thin Liquid Films by a Fluorescence Technique", Smart, A. E., et al.
Elings Virgil B.
Nicoli David F.
Marantz Sidney
Roston Ellsworth R.
Schwartz Charles H.
Wieder Stephen C.
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