Chemistry: molecular biology and microbiology – Apparatus – Differentiated tissue perfusion or preservation apparatus
Reexamination Certificate
2005-04-19
2005-04-19
Beisner, William H. (Department: 1744)
Chemistry: molecular biology and microbiology
Apparatus
Differentiated tissue perfusion or preservation apparatus
C435S286500, C435S293100, C623S912000, C623S915000, C623S916000
Reexamination Certificate
active
06881569
ABSTRACT:
An apparatus and method that allows the visualization of leakage of cell culture media through a conduit wall of a tissue-engineered biological construct such as a semilunar heart valve or valve graft under controlled physiologic conditions. The apparatus and method also allows for the assessment of valve function and intraluminal flow using conventional imaging modalities such as ultrasonic and magnetic resonance imaging. The apparatus allows the qualitative and quantitative evaluation of structural and functional characteristics of a condition tissue engineered construct prior to implantation using a valve housing and chamber and a flow-pressure simulator.
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Mayer, Jr. John E.
Perry Tjorvi Ellert
Sutherland Fraser W. H.
Beisner William H.
Children's Medical Center Corporation
Nixon & Peabody LLP
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