Apparatus and method for electroporation of biological samples

Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S285200, C514S04400A

Reexamination Certificate

active

07141425

ABSTRACT:
The present invention relates to methods and apparatus for the encapsulation of biologically-active substances in various cell populations. More particularly, the present invention relates to a method and apparatus for the encapsulation of biologically-active substances in various cell populations in blood by electroporation to achieve therapeutically desirable changes in the physical characteristics of the various cell populations in blood.

REFERENCES:
patent: 2955076 (1960-10-01), Gossling
patent: 3676325 (1972-07-01), Smith et al.
patent: 4075076 (1978-02-01), Xylander
patent: 4081340 (1978-03-01), Zimmermann et al.
patent: 4192869 (1980-03-01), Nicolau et al.
patent: 4252628 (1981-02-01), Boulton et al.
patent: 4321259 (1982-03-01), Nicolau et al.
patent: 4440386 (1984-04-01), Achelpohl
patent: 4473563 (1984-09-01), Nicolau et al.
patent: 4476004 (1984-10-01), Pohl
patent: 4478824 (1984-10-01), Franco et al.
patent: 4622302 (1986-11-01), Sowers
patent: 4652449 (1987-03-01), Ropars et al.
patent: 4663292 (1987-05-01), Wong et al.
patent: 4695547 (1987-09-01), Hilliard et al.
patent: 4699881 (1987-10-01), Matschke
patent: 4752586 (1988-06-01), Ropars et al.
patent: 4764473 (1988-08-01), Matschke et al.
patent: 4784737 (1988-11-01), Ray et al.
patent: 4800163 (1989-01-01), Hibi et al.
patent: 4804450 (1989-02-01), Mochizuki et al.
patent: 4822470 (1989-04-01), Chang
patent: 4840714 (1989-06-01), Littlehales
patent: 4849089 (1989-07-01), Marshall, III
patent: 4849355 (1989-07-01), Wong
patent: 4874690 (1989-10-01), Goodrich, Jr. et al.
patent: 4882281 (1989-11-01), Hilliard et al.
patent: 4906576 (1990-03-01), Marshall, III
patent: 4910140 (1990-03-01), Dower
patent: 4923814 (1990-05-01), Marshall, III
patent: 4931276 (1990-06-01), Franco et al.
patent: 4945050 (1990-07-01), Sanford et al.
patent: 4946793 (1990-08-01), Marshall, III
patent: 4956288 (1990-09-01), Barsoum
patent: 4970154 (1990-11-01), Chang
patent: 4995957 (1991-02-01), Ziegler et al.
patent: 5007995 (1991-04-01), Takahashi et al.
patent: 5036006 (1991-07-01), Sanford et al.
patent: 5043261 (1991-08-01), Goodrich et al.
patent: 5098843 (1992-03-01), Calvin
patent: 5100627 (1992-03-01), Buican et al.
patent: 5100792 (1992-03-01), Sanford et al.
patent: 5114681 (1992-05-01), Bertoncini et al.
patent: 5124259 (1992-06-01), Tada
patent: 5128257 (1992-07-01), Baer
patent: 5134070 (1992-07-01), Casnig
patent: 5135667 (1992-08-01), Schoendorfer
patent: 5137817 (1992-08-01), Busta et al.
patent: 5139684 (1992-08-01), Kaali et al.
patent: 5232856 (1993-08-01), Firth
patent: 5424209 (1995-06-01), Kearney
patent: 5501662 (1996-03-01), Hofmann
patent: 5545130 (1996-08-01), Hofmann et al.
patent: 5612207 (1997-03-01), Nicolau et al.
patent: 5676646 (1997-10-01), Hofmann et al.
patent: 5720921 (1998-02-01), Meserol
patent: 5728281 (1998-03-01), Holmström et al.
patent: 6074605 (2000-06-01), Meserol et al.
patent: 6090617 (2000-07-01), Meserol
patent: 6485961 (2002-11-01), Meserol
patent: 2001/0001064 (2001-05-01), Holaday
patent: AU 680890 (1994-10-01), None
patent: 2214800 (2002-02-01), None
patent: 1195997 (1998-10-01), None
patent: 2405119 (1975-09-01), None
patent: 3603029 (1987-08-01), None
patent: 4440386 (1996-05-01), None
patent: 0137504 (1985-04-01), None
patent: 0343783 (1989-11-01), None
patent: 0362758 (1990-04-01), None
patent: 0472772 (1992-03-01), None
patent: 0798309 (1997-10-01), None
patent: 62151174 (1987-07-01), None
patent: 62171687 (1987-07-01), None
patent: 62228277 (1987-10-01), None
patent: 62265975 (1987-11-01), None
patent: 63141587 (1988-06-01), None
patent: 1141582 (1989-06-01), None
patent: 2131584 (1990-05-01), None
patent: 2131585 (1990-05-01), None
patent: 2186993 (1990-07-01), None
patent: 3195485 (1991-08-01), None
patent: 4027393 (1992-01-01), None
patent: 6349068 (1994-12-01), None
patent: 7180029 (1995-07-01), None
patent: 7320720 (1995-12-01), None
patent: WO 88/04322 (1988-06-01), None
patent: WO 89/02464 (1989-03-01), None
patent: WO 89/03426 (1989-04-01), None
patent: WO 91/18103 (1991-11-01), None
patent: WO 94/21117 (1994-09-01), None
patent: WO 96/28199 (1996-03-01), None
patent: WO 98/24490 (1998-06-01), None
patent: WO 01/24830 (2001-04-01), None
Verma et al., Nature, vol. 389, 1997, pp. 239-242.
Anderson, Nature, vol. 392 supplement, 1998, pp. 25-30.
Juengst, BMJ, vol. 326, 2003, pp. 1410-1411.
“Advanced Coatings for the Medical Industry,” Multi-Arc Scientific Coatings, Copyright © Andal Corp.
“Biological Buffers,” In:The Biological Engineering Handbook,Bronzino (ed.), CRC Press, pp. 1650, c1995.
“Ion Bond® 16 Zirconium Nitride Coating,” Multi-Arc, Inc., 1996.
“Ion Bond® 17 Titanium Aluminum Nitride Coating,” Multi-Arc, Inc., 1995.
“Ion Bond® 19 Chromium Nitride Coating,” Multi-Arc, Inc., 1995.
“Ion Bond® Coatings for Instruments, Design Considerations,” Multi-Arc, Inc., 1995.
“Ion Bond® Coatings for Instruments, Most Commonly Asked Questions,” Multi-Arc, Inc., 1995.
“Preparation of certain reagents, anticoagulants and preservative solutions,” In:Practical Haematology,5thEdition, Dacie and Lewis (eds.), Appendicies, pp. 598, 1975.
“The Ion Bond Network,” Multi-Arc, Inc., 1995.
Abatti et al., “Development of a new geometrical form of micropipette: electrical characteristics and an application as a potassium ion selective electrode,”IEEE Trans. Biomed. Eng.,39:43-48, 1992.
Asakami et al., “Materials for electrode of alkali metal thermoelectric converter (AMTEC) (II),”J. Mater. Sci. Lett.,9(8):892-894, 1990.
Behrndt and Lunk, “Biocompatibility of TiN preclinical and clinical investigations,”Materials Sciences&Engineering,A139:58-60, 1991.
Capizzi et al., “Amifostine mediated protection of normal bone marrow from cytotoxic chemotherapy,”Cancer,72:3495-3501, 1993.
Chassy et al., “Transformation of bacteria by electroporation,”Trends in Biotechnology,6(12):303-309, 1988.
Coll et al., “Metallurgical and Tribological modification of titanium and titanium alloys by plasma assisted techniques,”Workshop H Society for Biomaterials Implat Retrieval Symposium,Sep. 17, 1992.
Dunican and Shivnan, “High frequency transformation of whole cells of amino acid producing coryneform bacteria using high voltage electroporation,”Bio/Technology,7:1067-1070, 1998.
Egorov and Noikova, “Effect of phase composition of TiN-Ni sintered electrode materials of characteristics of the ESA process,”Sov. Powder Metall Met Ceram.,29(9):705-710, 1991.
Einck and Holaday, “Enhancement of tissue oygenation by intracellular introduction of inositol hexaphosphate by flow electroporation of red blood cells,” In:Tissue Oxygenation in Acute Medicine(Update in Intensive Care and Emergency Medicine,33), Sibbald et al., (eds.), pp. 357-374, c1998.
Gersonde and Nicolau, “Enhancement of the O2release capacity and of the Bohr-effect of human red blood cells after incorporation of inositol hexaphosphate by fusion with effector-containing lipid vesicles,” In:Origins of Cooperative Binding by Hemoglobin,277-282, 1982.
Gersonde and Nicolau, “Improvement of the red blood cell O2release capacity by lipid vesicle-mediated incorporation of inositol hexaphosphate,”Blut,39:1-7, 1979.
Gersonde and Nicolau, “Modification of the oxygen affinity of intracellular haemoglobin by incorporation of polyphosphates into intact red blood cells and enhanced O2release in the capillary system,”Biblthca Haemat.,46:81-92, 1980.
Gersonde and Weiner, “The influence of infusion rate on the acute intravenous toxicity of phytic acid, a calcium-binding agent,”Toxicology,22:279-286, 1982.
Hirai et al., “A new antitumor antibiotic, FR-900482”J. of Antibiotics,40/5:607-611, 1987.
Hofmann and Evans, “Eletronic genetic—physical and biological aspects of cellular electromanipulation,”IEEE Engi

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Apparatus and method for electroporation of biological samples does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Apparatus and method for electroporation of biological samples, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus and method for electroporation of biological samples will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3628787

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.