Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge
Patent
1987-01-16
1988-05-31
Niebling, John F.
Chemistry: electrical and wave energy
Processes and products
Electrostatic field or electrical discharge
204299R, G01N 2728, G01N 2726
Patent
active
047479191
ABSTRACT:
A method and apparatus are provided for electrophoresis of macromolecules. The macromolecules are separated through a tube gel which is connected to an upper electrode buffer reservoir by means of a liquid bridge. The tubes themselves are neither permanently attached nor removably attached to the apparatus but merely rest in and abut appropriate positioning devices. Formation and maintenance of the liquid bridge is promoted by means of hydrophobic surfaces. By balancing the hydrostatic pressure of the upper chamber upon the porous or perforated surface, with the surface tension of the liquid, no leakage from the upper chamber results except by means of the stable liquid bridges.
REFERENCES:
patent: 2843540 (1958-07-01), Ressler
patent: 3867271 (1975-02-01), Hoefer
patent: 4284491 (1981-08-01), Vesterberg
patent: 4305799 (1981-12-01), Schwarz et al.
Ornstein, "Disc Electrophoresis-I: Background and Theory", Annals of the New York Academy of Sciences, vol. 121, pp. 321-349 (1964).
Davis, "Disc Electrophoresis-II: Method and Application to Human Serum Proteins", Annals of the New York Academy of Sciences, vol. 121, pp. 404-427 (1964).
Anderson et al, "Analytical Techniques for Cell Fractions XXI, Two-Dimensional Analysis of Serum and Tissue Proteins: Multiple Isoelectric Focusing", Analytical Biochemistry, vol. 85, pp. 331-340 (1978).
Large Scale Biology Corporation
Niebling John F.
Starsiak John S.
LandOfFree
Apparatus and method for electrophoresis in tubes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Apparatus and method for electrophoresis in tubes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus and method for electrophoresis in tubes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1872600