Optics: measuring and testing – Blood analysis
Patent
1996-11-26
1998-08-25
Rosenberger, Richard A.
Optics: measuring and testing
Blood analysis
356 72, 356336, 356343, G01N 2147, G01N 3349
Patent
active
057988277
ABSTRACT:
The present invention provides an apparatus and method to determine individual red blood cell shape within a flow cytometric aperture. Cell shape is determined by measuring the asymmetry of a light scatter pattern produced by laser illumination of the cell within the aperture by light scatter detectors which collect light from specific angular regions of light scatter, and analyzing the asymmetry of the light scatter patters to determine the individual red blood cell shape. Embodiments of the invention further provide for the determination of red blood cell shape by measuring the asymmetry of a light scatter pattern and measuring electrical resistance of the red blood cell.
REFERENCES:
patent: 4606636 (1986-08-01), Monin et al.
Frank Robert S.
Gong Weiyan
Leif Robert C.
Rodriguez Carlos M.
Wyatt James L.
Alter Mitchell E.
Coulter International Corp.
Rosenberger Richard A.
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