Apparatus and method for detecting microorganisms

Details Apparatus and method for detecting microorganisms Apparatus and method for detecting microorganisms

2006-10-31

2006-10-31

Redding, David (Department: 1744)

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

C073S579000, C324S750010, C324S754120, C435S006120

Reexamination Certificate

active

07129081

ABSTRACT:
The present invention relates to the fast detection of microorganisms, i.e. of bacteria, fungi, cells and other organisms, making use of methods and apparatuses coming from nanotechnology. According to the present invention, such organisms are detected using micromechanical sensor means known from many physical and chemical applications. One or more micromechanical cantilever sensors are either coated with a nutritive medium or at least partially built from a nutritive medium. By depositing a microorganism on the cantilever surface, preferably in a targeted way and in a controlled dosage, a “biological reaction” is started. This reaction results in a change of the mechanical and/or electrical properties of the sensor, i.e. the cantilever. These changes are determined, preferably at certain points in time, and thus allow the detection and detailed observation of the applied microorganism.

REFERENCES:
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Prescesky, “Silicon micromachining technology for sub-nanogram discrete mass resonant biosensors,” Canadian Journal of Phys., vol. 70, Aug. 7-13, 1992, pp. 1178-1183.
Ilic, “Single cell detection with micromechanical oscillators,” J. Vac. Sci. Technol. B., vol. 19, No. 6, Nov. 1, 2001, pp. 2825-2828.
European Search Report for EP 03 40 5136.

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