Apparatus and method for detecting genetic mutations and...

Details Apparatus and method for detecting genetic mutations and... Apparatus and method for detecting genetic mutations and...

2007-10-09

2007-10-09

Whisenant, Ethan (Department: 1634)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C536S063000, C536S024300

Reexamination Certificate

active

10949761

ABSTRACT:
A method and means of identifying nucleic acid oligomers is disclosed. A sample is split into parts and the parts are flowed through chromatography columns containing nucleic acid oligomer probes bound to a binding medium. Analyte oligomers are transiently hybridized to complementary probe oligomers during chromatography. Detection and analysis of oligomer peaks is used to identify the oligomers contained in the sample.

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Anada, T. et al Anal. Sci. Jan. 2003; 19(1):73-7 Oligodeoxynucleotide-modified Capillary for Electrophoretic Separation of Single-Stranded DNAs with a Single-Base Difference.

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