Apparatus and method for delivery of surgical and therapeutic ag

Details Apparatus and method for delivery of surgical and therapeutic ag Apparatus and method for delivery of surgical and therapeutic ag

1997-10-21

1999-12-07

Coggins, Wynn Wood

Surgery

Means for introducing or removing material from body for...

Infrared, visible light, ultraviolet, x-ray or electrical...

604 21, A61N 130

Patent

active

059998474

ABSTRACT:
Localized, transient pressure waves are applied to tissue adjacent to target cells by means of a light source and a coupling interface placed in contact with the tissue that converts light from the light source into acoustic energy. The pressure waves cause transient poration of the cell membranes. The therapeutic agents are delivered to the site of the localized pressure waves by any suitable means, such as by injection with a needle. The light source and coupling interface can be incorporated into a catheter for application of the pressure waves to diseased blood vessels. A manually manipulable surgical device incorporating a needle for injecting the agent, light source, and coupling interface is also described.

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