Apparatus and method for controllably affecting the...

Radiant energy – Ionic separation or analysis – Static field-type ion path-bending selecting means

Reexamination Certificate

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C250S288000, C250S281000, C250S282000, C250S286000, C250S292000, C250S290000

Reexamination Certificate

active

07112788

ABSTRACT:
An apparatus for separating ions includes providing a FAIMS analyzer region defined by a space between a first electrode surface and a second electrode surface and extending between an ion inlet end and an ion outlet end. An asymmetric waveform is applied to the first electrode surface and a compensation voltage difference is applied between the first and second electrode surfaces. An output signal is provided from a temperature sensor, the output signal relating to a temperature within the FAIMS analyzer region. In dependence upon the output signal, the temperature within the FAIMS analyzer region is controllably affected. The apparatus supports operation of FAIMS at temperatures different from the temperature of other components in a tandem multi-stage system, and supports the stable operation of FAIMS at different temperatures which increases the separation capability of FAIMS.

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Viehland et al., “Comparison of High-Field Ion Mobility Obtained from Drift Tubes and a FAIMS Apparatus”, Int'l Journal of Mass Spectrometry, No. 197, pp. 123-130, Elsevier Science B.V., 2000.

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