Chemistry: molecular biology and microbiology – Apparatus – Bioreactor
Reexamination Certificate
2006-04-04
2006-04-04
Ketter, James (Department: 1636)
Chemistry: molecular biology and microbiology
Apparatus
Bioreactor
C435S297400, C435S299200
Reexamination Certificate
active
07022518
ABSTRACT:
A co-culture apparatus and method for, among other things, converting a progenitor cell line into a target cell line. The apparatus comprises an exterior receptacle, a removable cartridge that fits into the exterior receptacle, and a closure member to seal the apparatus. The invention is also directed to a method for transforming a progenitor cell line into a target cell line. In one embodiment of the invention, the method comprises the steps of: establishing a progenitor cell line; establishing a support cell line; co-culturing said progenitor and support cell lines; establishing a transformation cell line; and co-culturing said progenitor and transformation cell lines, wherein the transformation cell line supports the transformation of the progenitor cell line into a target cell line.
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Ketter James
Wood Christopher
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