Apparatus and method for automatically performing peritoneal equ

Liquid purification or separation – Processes – Including controlling process in response to a sensed condition

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210 85, 210 86, 210 97, 210252, 210646, 604 29, A61M 128

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active

056700571

ABSTRACT:
There is disclosed a method and apparatus for automatically conducting peritoneal equilibration testing. The method involves removing a sample of overnight dwell fluid from a patient in an amount sufficient to determine the concentration of a metabolite in the drain fluid. The concentration of the metabolite in the sample is then detected and the overnight dwell fluid is drained and weighed. A known weight of dialysate fluid is instilled into a patient and thereafter there are periodically withdrawn samples of the dialysate fluid and the concentration of metabolite in each sample is determined. The ratio of metabolite concentration of each of the periodically drawn samples to metabolite concentration for the overnight dwell fluid is determined. The patient is then drained after a predetermined dwell time and the volume of drained dialysate is determined. The mass transfer area coefficient of the patient's peritoneal membrane is then obtained as a function of the measured variables. Means are provided for conducting the method for each of the steps described.

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"Membrane Phenomena and Mass Transfer Kinetics in Peritoneal Dialysis" in the Journal of Membrane Science by Michael J. Lysaght and Peter C. Farrell, vol. 44, pp. 5-33 (1989).

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