Chemistry: analytical and immunological testing – Automated chemical analysis – Condition or time responsive
Patent
1988-02-19
1990-04-24
Marcus, Michael S.
Chemistry: analytical and immunological testing
Automated chemical analysis
Condition or time responsive
436 51, 436 43, 422 75, 422 76, 422 81, 422 82, 422130, G01N 3500, G01N 3116
Patent
active
049200569
ABSTRACT:
Apparatus and method for automatic microbatch reaction including a reactor having a reaction chamber, such as a 1.5 milliliter plastic centrifuge tube having a conical bottom. An automatically actuated injection valve is used to inject less than 1 milliliter of a sample into the reaction chamber. One or more automatically actuated reagent valves are used to introduce respective pressurized reagents into the reaction chamber to process the sample. The volume of the reagent(s) introduced into the reaction chamber is less than 1 milliliter and controlled by the on time of the respective reagent valve. The automatically actuated valves are controlled by a computer based timer. A sensor positioned in the chamber, such as a pH electrode, can be used to analyze the processed sample in place or the processed sample can be analyzed by flowing it from the reaction chamber through a flow-through detector, such as a flow-through spectrophotometer.
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Griffith Jr. D. John
Halldorson Burke M.
Marcus Michael S.
Stevens Timothy S.
The Dow Chemical Company
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