Chemistry: analytical and immunological testing – Automated chemical analysis
Reexamination Certificate
2004-03-24
2010-06-15
Alexander, Lyle A (Department: 1797)
Chemistry: analytical and immunological testing
Automated chemical analysis
C436S063000, C436S180000, C422S062000, C422S068100
Reexamination Certificate
active
07736901
ABSTRACT:
This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.
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Cheadle Rhonda J.
Lauks Imants R.
Maczuszenko Andrezej
Opalsky Cindra A. Widrig
Opalsky David
Abbot Point Of Care Inc.
Alexander Lyle A
Katten Muchin & Rosenman LLP
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