Apparatus and method for analyzing polynucleotide sequences and

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

422 50, 422 52, 422 55, 422 56, 422 57, 422 681, 422 69, 422 71, 422 8205, 422 8206, 422 8207, 422 8208, 422 99, 536 253, 935 77, 935 78, C12Q 168, C07H 2100, C07H 2102, C07H 2104

Patent

active

057006377

ABSTRACT:
This invention provides an apparatus and method for analyzing a polynucleotide sequence; either an unknown sequence or a known sequence. A support, e.g. a glass plate, carries an array of the whole or a chosen part of a complete set of oligonucleotides which are capable of taking part in hybridization reactions. The array may comprise one or more pair of oligonucleotides of chosen lengths. The polynucleotide sequence, or fragments thereof, are labelled and applied to the array under hybridizing conditions. Applications include analyses of known point mutations, genomic fingerprinting, linkage analysis, characterization of mRNAs, mRNA populations, and sequence determination.

REFERENCES:
patent: 4216245 (1980-08-01), Johnson
patent: 4327073 (1982-04-01), Huang
patent: 4395486 (1983-07-01), Wilson et al.
patent: 4563419 (1986-01-01), Ranki et al.
patent: 4656127 (1987-04-01), Mundy
patent: 4704353 (1987-11-01), Humphries et al.
patent: 4728502 (1988-03-01), Hamill
patent: 5002867 (1991-03-01), Macevicz
patent: 5164319 (1992-11-01), Hafeman et al.
patent: 5202231 (1993-04-01), Drmanac et al.
Tenover, Clinical Microbiology Reviews, 1(1), 82-101 (Jan. 1988).
Ogle et al., The Journal of Infectious Diseases, 155(1), 119-126 (Jan. 1987).
Moseley et al., Advances in Research on Cholera and Related Diarrheas, 207-216 (1983).
Frankel et al., The Journal of Infectious Diseases, 161 1252-1256 (1990).
Ezaki, Asian Med. J., 34(8), 454-459 (1991).
Ezaki et al., Cancer, 61, 106-109 (1988).
Robins-Browne et al., Journal of Clinical Microbiology, 27(4), 644-650 (Apr. 1989).
Ezaki et al., International Journal of Systematic Bacteriology, 36(2), 345-347 (1986).
McDonough et al., Journal of Clinical Microbiology, 26(12), 2515-2519 (1988).
Buneman et al. Nucleic Acids Research, 10(22), 7163-7180 (1982).
Foreter et al. Nucleic Acids Research, 13(3), 745-761 (1985).
Koomey et al., Infection and Immunity, 43(1), 101-107 (Jan. 1984).
Syvanen, Medical Biology, 64, 313-324 (1986) (Review Article).
Nagata et al., FEBS Letters, 183(2), 379-382 (Apr. 1985).
Ezaki et al., FEMS Microbiology Letters, 67, 127-130 (1990).
Kilpper-Balz et al., System. Appl. Microbiol., 5, 494-500 (1984).
Habermehl, Ed., Rapid Methods and Automation in Microbiology and Immunology, 30-33 (1985).
Schachter, Diagn. Microbiol. Infect. Dis., 4, 185-189 (1986).
Starnbach, Journal of Clinical Microbiology, 27(6), 1257-1261 (Jun. 1989).
Ezaki et al., Microbiol. Immunol., 32(2), 141-150 (1988).
Ezaki et al., J. Gen. Appl. Microbiol., 34, 191-199 (1988).
Ezaki et al., Journal of Clinical Microbiology, 26(9), 1708-1713 (Sep. 1988).
Farrow et al., System Appl. Microbiol., 5, 467-482, 483-493 (1984).
Dean et al., Journal of Clinical Microbiology, 27(5), 1062-1067 (May 1989).
Shash et al. Nucleic Acids Research, 15(13), 5353-5372 (1987).
Gingeras et al. Nucleic Acids Research, 15(13), 5373-5390 (1987).
Church et al., Science, 240, 185-188 (Apr. 8, 1988).
Buneman Nucleic Acids Research, 10(22), 7181-7196 (1982).
Brigati et al. (1983) Virology, vol. 126 pp. 32-50.
Saiki et al. (1986) Nature, vol. 324, pp. 163-166.
Wood et al. (1985) Proc. Natl Acad. Sci (USA), vol. 82, pp. 1585-1588.
Fodor et al. (1991) Science, vol. 251, pp. 767-773.
G. Beltz et al., Methods in Enzymology, 100, 266-285 (1983).
E.M. Southern et al., Genomics, 13, 1008-1017(1992).
Y.P. Lysov et al., Dokl. Akad., 303, 1508-1511(1988).
F. Kafatos et al., Nucleic Acids Research, 7(6), 1541-1552 (1979).
H.M. Geysen et al., J. Immun. Meth., 102, 259-274(1987).
V.J. Kidd et al., Nature, 304, 230-234(1983).
P. Masinkowski et al., Nucleic Acids Research, 10(24), 7895-7903 (1982).
G.K. Sim et al., Cell, 18, 1303-1316(1979).
W. Bains et al., J. Theor. Biol., 135, 303-307(1988).
U.B. Voss et al., Biochemical Society Transactions, 624th Meeting, Dublin, 216-217 (1987).
L.J. Arnold et al., Federation Proceedings, 43(7), Abstract No. 3669(1984).
T. Maniatis et al., Molecular Cloning, A Laboratory Manual, Cold Spring Harbor Laboratory, p. 282 (1982).
C.R. Cantor et al., Genomics, 13, 1378-1383(1992).
G.M. Church et al., Proc. Natl. Acad. Sci. USA, 81 1991-1995(1984).
R. Frank, Methods in Enzymology, 154, 221-251(1987).
R. Frank, Nucleic Acids Research, 11(13), 4365-4377(1983).
A.R. Brautigam et al., J. Clin. Microbiol., 12(2), 226-234(1980).
A. Rosenthal et al., Nucleic Acids Research, 13(4), 1173-1184(1985).
B. Lewin, Genes, 3rd Ed., John Wiley & Sons, pp. 360-362(1983).
M. Anderson et al., Nucleic Acid Hybridisation, A Practical Approach, B.D Hames et al., eds., IRL Press, pp. 73-111 (1985).
M.S. Urdea et al., Gene, 61, 253-264 (1987).
C.G. Miyada et al., Methods in Enzymology, 154, 94-107 (1987).
E. Calva et al., J. Biol. Chem., 255(22), 11011-11016(1980).
A.R. Dunn et al., Cell, 12, 23-36 (1977).
G. Wengler et al., Virology, 78, 124-134 (1977).
J.M. Coffin et al., Cell, 13 761-773(1978).
A. Palva et al., DNA, 7(2), 135-142(1988).
R. Drmanac et al., "Sequencing of Megabase Plus DNA by Hybridization: Theory of the Method", University of Belgrade (former Yugoslavia) (1988).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Apparatus and method for analyzing polynucleotide sequences and does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Apparatus and method for analyzing polynucleotide sequences and , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Apparatus and method for analyzing polynucleotide sequences and will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1801704

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.