Apovincaminol derivative and compositions and methods utilizing

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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546 51, A61K 31435, C07D46100

Patent

active

044242247

ABSTRACT:
The invention relates to the new apovincaminol-3',4',5'-trimethoxy-benzoate and acid addition salts thereof.
The new compound may be prepared by reacting apovincaminol or an acid addition salt thereof with 3,4,5-trimethoxy benzoic acid or a reactive derivative thereof capable of acylation and if desired converting the compound thus obtained into an acid addition salt.
The new compound of the present invention can be used in therapy in the treatment of skin diseases attached to pathological cell proliferation and in the propylaxis of such diseases.

REFERENCES:
patent: 4065458 (1977-12-01), Lorincz et al.
patent: 4328231 (1982-05-01), Zajer nee Balazs et al.
Lorincz et al., Chemical Abstracts, vol. 82, 129279v (1975).
Arzneimittel Forschung, vol. 26, No. 10, Rosdy et al., pp. 1923-1926 (1976).

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