Apovincaminic acid derivatives

Details Apovincaminic acid derivatives Apovincaminic acid derivatives

1989-09-12

1990-12-25

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D46100, A61K 31435

Patent

active

049804740

ABSTRACT:
An apovincaminic acid derivative represented by the formula ##STR1## wherein n is an integer of from 2 to 11, and a pharmaceutically acceptable salt thereof are disclosed. These compounds are useful for therapy of cerebrovascular injuries, peripheral vessel injuries, angina pectoris, hypertension and senile dementia.

REFERENCES:
patent: 3966745 (1976-06-01), Guidicelli et al.
patent: 4540701 (1985-10-01), Ueda et al.
patent: 4613608 (1986-09-01), Ueda et al.
patent: 4839362 (1989-06-01), Kreidl et al.
Ban et al., "Apovincaminic Acid Esters", CA 105: 43143c (1986).

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