Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-06-06
2006-06-06
Owens, Amelia A. (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S284000
Reexamination Certificate
active
07057044
ABSTRACT:
The invention provides aporphine and oxoaporphine compounds that have endothelial nitric oxide synthase (eNOS) maintaining or enhancing activities and may be used to manufacture a medicaments for preventing or treating ischemic diseases in human and mammal, and the ischemic diseases may include ischemic cerebral apoplexy, ischemic cerebral thrombosis, ischemic cerebral embolism, hypoxic ischemic encephlopathy, ischemic cardiac disease or ischemic enteropathy etc.
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Li-Man Hung, et al. “Thaliporphine Protects Ischemic and Ischemic-Reperfused Rat Hearts Via an NO-Dependent Mechanism” Drug Development Research 52:446-453 (2001).
Lee Shoei-Sheng
Su Ming-Jai
Lotus Pharmaceutical Co., Ltd.
Osha & Liang LLP
Owens Amelia A.
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